Author

Alan McLachlan

University of Illinois ChicagoORCID 0000-0002-4168-2365Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Adam Oberstein· 1 shared Mariana Andrade-Medina· 1 shared Preethi Golconda· 1 shared Rachel Matrenec· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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1 shared paperMicrobiology

Adam Oberstein

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1 paper

Recent·Most cited

The Epithelial-to-Mesenchymal Transition Supports HCMV Infection and Biosynthesis in Mammary Epithelial Cells Through Two Distinct Mechanisms.

Preethi Golconda, Mariana Andrade-Medina, Rachel Matrenec, Alan McLachlan, Adam Oberstein

This study shows that inducing epithelial-to-mesenchymal transition in mammary epithelial cells restores HCMV biosynthesis through two distinct mechanisms: enhanced viral entry and enhanced mRNA translation.

bioRxiv · Aug 12, 2024 · PreprintMicrobiology