The Epithelial-to-Mesenchymal Transition Supports HCMV Infection and Biosynthesis in Mammary Epithelial Cells Through Two Distinct Mechanisms.
Preethi Golconda, Mariana Andrade-Medina, Rachel Matrenec, Alan McLachlan, Adam Oberstein
This study shows that inducing epithelial-to-mesenchymal transition in mammary epithelial cells restores HCMV biosynthesis through two distinct mechanisms: enhanced viral entry and enhanced mRNA translation.
bioRxiv · Aug 12, 2024 · PreprintMicrobiology