Uli Klümper

Plasmid-plasmid interactions reshape extracellular vesicle cargo and gene transfer potential

This study shows that plasmid-plasmid interactions alter EV cargo composition and gene transfer potential in microbial communities.

Microbial community diversity predicts invasion resistance of freshwater biofilms against antibiotic-resistant bacteria

The paper shows that microbial diversity in river biofilms predicts resistance to invasion by antibiotic-resistant bacteria, with higher diversity reducing the likelihood of establishment.

Resistance to the conjugation inhibitor AZT reveals mating partner incompatibility during plasmid transfer

This study shows that AZT resistance in bacterial mating partners affects plasmid transfer efficiency, revealing that resistance reshapes physiological compatibility between partners.

Cycles of contamination and recovery: Combined sewer overflows drive acute but transient antimicrobial resistance exposure in an urban stream

This study quantifies how combined sewer overflows (CSOs) temporarily increase antimicrobial resistance in urban streams but do not establish long-term resistance due to rapid washout.

Reusable immobilised quaternary ammonium particles reduce microbial and resistome burdens without promoting resistance selection during wastewater post-treatment.

This paper evaluates immobilized BDMDAC particles for wastewater treatment, showing they reduce microbial and ARG burdens without promoting resistance selection.

Selective spread of mobile antibiotic resistance genes in wastewater microbiomes driven by the non-antibiotic pharmaceutical carbamazepine

This study shows that carbamazepine promotes the spread of specific antibiotic resistance genes in wastewater microbiomes through horizontal gene transfer and direct selection.

Environmental reservoir of resistance genes for the last resort antibiotic Cefiderocol.

This study identifies cefiderocol resistance genes in environmental samples using functional metagenomics, revealing beta-lactamases and mobile genetic elements.

Suppressing selection for antibiotic resistance in the environment: A transparent, ecology-based approach to predicted no-effect concentrations

The paper proposes an ecology-based method to predict no-effect concentrations for antibiotic resistance using MIC data and fitness cost estimates, suggesting regulatory thresholds should be lowered.

Fish are poor sentinels for surveillance of riverine AMR

This study finds that fish are not effective sentinels for detecting AMR pollution from wastewater treatment plants, as their resistomes do not reflect increases in ARGs in river water and sediment.

Jellyfish blooms - an overlooked hotspot and potential vector for the transmission of antimicrobial resistance in marine environments

This study shows that jellyfish blooms create a hotspot for antimicrobial resistance gene (ARG) transmission by promoting microbial growth and horizontal gene transfer in marine environments.

Drivers of antibiotic resistance in two monsoon-impacted Indian urban rivers receiving untreated wastewater

The paper investigates the drivers of antibiotic resistance in two Indian rivers, finding that untreated wastewater is the main source of ARGs rather than heavy metal co-selection.