Eugenia Cammarota

The paper identifies the proline-rich domain (PRD) of HTT exon 1 as a modifier of neuronal toxicity in Huntington's disease, showing that the human PRD exacerbates while the mouse PRD mitigates toxicity.

MicroSplit uses deep learning to computationally unmix fluorescent microscopy data, enabling faster imaging and reduced photon exposure by separating multiple cellular structures from a single channel.