Author

Jinsook Ahn

Korea Advanced Institute of Science and TechnologyORCID 0000-0002-4175-5181Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 2 Biochemistry· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Approach:deep learning· 2 Approach:diffusion model· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:protein design· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Dong Sun LeeiD· 2 shared Ho Min KimiD· 2 shared Inseong JoiD· 2 shared Nam‐Chul HaiD· 2 shared Ryeongeun ChoiD· 2 shared Bum-Joon ParkiD· 1 shared Byungil KimiD· 1 shared Donghyeok MaiD· 1 shared

Activity by Year

2020-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersBioengineering

Dong Sun LeeORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

ProteinSketch translates spatial intuition into protein design with bimanual interaction in VR

Donghyeok Ma, Junyup Lee, H. C. Lee, Sang-Hyun Lee, Yeong Gyeong Oh, Ye-eun Kim, Taegyu Jin, Siripon Sutthiwanna, Seung-Jun Lee, Woosung Jeon, Dong Sun Lee, Jinsook Ahn, Ryeongeun Cho, H C Park, Seongin Jeong, , Ho Min Kim

ProteinSketch enables interactive protein design in VR by translating spatial intuition into constraints for AI-driven protein structure generation.

bioRxiv · Jul 20, 2026 · PreprintBioengineering

Structural basis for HKU5-CoV main protease inhibition by the clinical antivirals nirmatrelvir and ensitrelvir

Hyun Kim, Jinsook Ahn, Juyeon Lee, Seungheon Jung, Ji Woo Kim, Byungil Kim, Nam‐Chul Ha, Inseong Jo

This study determines the crystal structures of HKU5-CoV Mpro with and without inhibitors, revealing conserved binding mechanisms and informing antiviral drug development.

bioRxiv · Jul 2, 2026 · PreprintBiochemistry

De novo and scaffold-based design of GDF15 binders for cancer cachexia diagnostics and therapeutics

Jinsook Ahn, Ryeongeun Cho, S. B. Kim, Dong Sun Lee, Ho Min Kim

This paper designs high-affinity GDF15 binders using AI-driven methods for cancer cachexia diagnostics and therapeutics, showing potent neutralization and biosensing capabilities.

Experimental & Molecular Medicine · May 8, 2026Peer-reviewedBioengineering

Separation of coiled-coil structures in lamin A/C is required for elongation of the filament

Jinsook Ahn, Soyeon Jeong, So‐mi Kang, Inseong Jo, Bum-Joon Park, Nam‐Chul Ha

This study investigates how mutations affecting the eA22 interaction in lamin A/C impact the separation of coiled-coil structures and filament elongation.

Cells · Dec 31, 2020Peer-reviewedMolecular Biology