Author

Yicheng Weng

Shanghai Jiao Tong UniversityORCID 0000-0002-4192-0917Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Man PaniD· 2 shared Qingyun ZhengiD· 2 shared Yuanyuan YuiD· 2 shared Yujuan Duan· 2 shared Anthony A. KossiakoffiD· 1 shared Chunyan HaniD· 1 shared Jingxian LiiD· 1 shared Lei LiuiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

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10 top collaborators · 40 mutual co-author links

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2 shared papersBiochemistry

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintFeb 27, 2026

Faf2/Ubx2 potentiates p97/Cdc48 segregase activity via functional priming and reinforcement of the UT3 domain in Ufd1

Y T Ren, Qingyun Zheng, Yujuan Duan…·Lei Liu

This study shows Faf2/Ubx2 enhances p97/Cdc48 segregase activity by remodeling its substrate recognition module and priming its motor engagement, enabling efficient substrate processing.

1 citation

proteomicsexperimental assay

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BiochemistrybioRxivPreprintDec 18, 2025

Conformation-specific Antibody Deciphers K27-linked Ubiquitination in Chaperone-Mediated Proteostasis

Chunyan Han, Yicheng Weng, Qingyun Zheng…·Yuanyuan Yu

This paper develops a conformation-specific antibody, K27-IgG, to detect K27-linked polyubiquitin and identifies DNAJB1 as a reader and UBE2Q1 as a writer for this ubiquitin chain type.

1 citation

humanproteomics

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