Dahai Luo

This study compares Z22 and Z-D11 antibodies' binding to Z-NA substrates, finding they have distinct specificities and functional capabilities.

This paper presents a cryo-EM structure of the Chikungunya virus replication complex, revealing two distinct RNA-binding sites involved in genome import and replication elongation.

This paper identifies potent benzamide compounds against Zika virus by targeting NS4B, showing superior potency and novel resistance mutation patterns compared to existing treatments.

The paper presents cryo-EM structures of anti-Z-DNA antibodies bound to Z-DNA, revealing their recognition mechanism and lack of B-to-Z transition induction.

This study shows that Chikungunya virus nsP1 preferentially binds to positively curved membranes, enabling saddle curvature association critical for replication complex assembly.

The paper reports crystal structures of alphavirus nsP4 RNA polymerase domains and identifies dynamic regions critical for RNA replication.

The paper introduces CapQuant, a mass spectrometry-based method to analyze RNA caps, revealing new cap structures and variations in humans and mice.