GeneticsPLoS BiologyPeer-reviewed
XDH-1 inactivation causes xanthine stone formation in C. elegans which is inhibited by SULP-4-mediated anion exchange in the excretory cell
Jennifer Snoozy, Sushila Bhattacharya, Brandon Johnson…·Kurt Warnhoff
This paper identifies sulp-4 as a critical gene controlling xanthine stone accumulation in C. elegans by mediating sulfate transport, and shows its interaction with sulfur amino acid metabolism and osmotic stress pathways.
3 citations