Author

Kotaro Tanaka

Institute of Integrated Research, Institute of Science TokyoORCID 0000-0002-4205-0589Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

Frequent Co-Authors

Kouki NishikawaiD· 1 shared Naotaka TsutsumiiD· 1 shared Yoshinori FujiyoshiiD· 1 shared Yuki ShiimuraiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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1 shared paperBiophysics

Kouki NishikawaORCID

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1 paper

Recent·Most cited

Structural Insights into Biased Signaling at Chemokine Receptor CCR7

Kotaro Tanaka, Kouki Nishikawa, Yuki Shiimura, Yoshinori Fujiyoshi, Naotaka Tsutsumi

This paper presents cryo-EM structures of CCR7 with CCL19 and CCL21, revealing distinct binding modes and dynamic receptor conformations that underlie biased agonism and differential signaling outcomes.

Proceedings of the National Academy of Sciences · Apr 29, 2026Peer-reviewedBiophysics