Author

Yoshinori Fujiyoshi

Institute of Integrated Research, Institute of Science TokyoORCID 0000-0002-8070-1493Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:deep learning· 1 Organism:human· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

Frequent Co-Authors

Naotaka TsutsumiiD· 2 shared Asuka InoueiD· 1 shared Carl‐Mikael SuomivuoriiD· 1 shared Deepa Waghray· 1 shared K. Christopher GarcíaiD· 1 shared Kevin M. JudeiD· 1 shared Kotaro TanakaiD· 1 shared Kouki NishikawaiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiophysics

Naotaka TsutsumiORCID

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2 papers

Recent·Most cited

BiophysicsNature CommunicationsPeer-reviewedSep 28, 2026

Structural basis of stepwise G protein activation by the viral chemokine receptor US28

Kevin M. Jude, Carl‐Mikael Suomivuori, Deepa Waghray…·Naotaka Tsutsumi

The paper determines structural states of the US28-Gq complex to elucidate a stepwise G protein activation mechanism.

DOI 10.1038/s41467-026-78122-7

experimental assay

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BiophysicsProceedings of the National Academy of SciencesPeer-reviewedApr 29, 2026

Structural Insights into Biased Signaling at Chemokine Receptor CCR7

Kotaro Tanaka, Kouki Nishikawa, Yuki Shiimura…·Naotaka Tsutsumi

This paper presents cryo-EM structures of CCR7 with CCL19 and CCL21, revealing distinct binding modes and dynamic receptor conformations that underlie biased agonism and differential signaling outcomes.

2 citations

humanstructural biology

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