Author
Institute of Integrated Research, Institute of Science TokyoORCID 0000-0002-3617-7145Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
4 papers
Recent·Most cited
Kevin M. Jude, Carl‐Mikael Suomivuori, Deepa Waghray, Shoji Maeda, Yoshinori Fujiyoshi, Asuka Inoue, K. Christopher García, Naotaka Tsutsumi
The paper determines structural states of the US28-Gq complex to elucidate a stepwise G protein activation mechanism.
Nature Communications · Sep 28, 2026Peer-reviewedBiophysics
Qiaoyi Liang, Yasuka Toda, Pauline Affatato, Gentoku Kakizaki, Hitomi Kaname, Kayoko Suzuki, Tae Kuramoto, Meng‐Ching Ko, Maxime Policarpo, Julia F. Cramer, Akihiro Itoigawa, Keisuke Furumitsu, Keren R. Sadanandan, Shigehiro Kuraku, Atsuko Yamaguchi, , Maude W. Baldwin
This study investigates the evolutionary origin of sugar sensing in vertebrates, finding that it predates angiosperms and involves multiple independent T1R-based mechanisms.
bioRxiv · Aug 28, 2026 · PreprintEvolutionary Biology
Kotaro Tanaka, Kouki Nishikawa, Yuki Shiimura, Yoshinori Fujiyoshi, Naotaka Tsutsumi
This paper presents cryo-EM structures of CCR7 with CCL19 and CCL21, revealing distinct binding modes and dynamic receptor conformations that underlie biased agonism and differential signaling outcomes.
Proceedings of the National Academy of Sciences · Apr 29, 2026Peer-reviewedBiophysics
Rakuto Mizoguchi, Yasuka Toda, Mana Nagae, Takashi Yoshida, Hiroaki Matsuura, Kunio Hirata, Yohei Miyanoiri, Maiko Hosotani, Yuji Ashikawa, Chiaki Ito, Naotaka Tsutsumi, N. Yasui, Yoshiro Ishimaru, Atsuko Yamashita
This study determines the crystal structure of a pufferfish umami taste receptor ortholog, revealing how it binds both L- and D-amino acids through structural adaptations.
bioRxiv · Nov 24, 2025 · PreprintBiochemistry