GeneticsbioRxivPreprint
A non-mosaic humanized mouse model of Down syndrome, trisomy of the long arm of human chromosome 21 in mouse chromosome background
Yasuhiro Kazuki, Feng J. Gao, Yicong Li…·Roger H. Reeves
This paper describes a new non-mosaic humanized mouse model of Down syndrome with a nearly complete copy of the long arm of human chromosome 21.
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