Moore Z. Chen

This paper introduces a long-read sequencing method to directly quantify synthetic mRNA abundance, integrity, and host response in vivo.

This paper introduces an antibody capture system for LNPs that enhances mRNA delivery and gene expression by enabling precise targeting to T cells with minimal off-target effects.

The paper introduces an enAsCas12a mouse model and associated libraries for efficient gene editing and screening, identifying drug resistance genes and enabling simultaneous gene knockouts and activations.