ImmunologybioRxivPreprint
Exploring the immune environment of glioblastoma through single-cell RNA sequencing in humanized mouse models
Jun Takei, Ken Furudate, Yoshiko Nagaoka-Kamata…·Satoru Osuka
This paper establishes a humanized mouse model of glioblastoma using patient-derived xenografts to study immune infiltration and tumor heterogeneity, finding immune cell profiles similar to recurrent human GBM.