Masakazu Kamata

This study uses human iPSC-derived skin organoids to model fibrosis, identifies RUNX2 as a key driver, and finds a small molecule that suppresses fibrotic programs.

The paper shows that thalamic microglia engulfing synapses, driven by CD9 and FcγRIII signals, cause cognitive impairment after cortical injury.

This study shows that knocking down JNK in CAR-T cells increases their cytotoxicity against ovarian cancer by enhancing granzyme B expression through NFATc1.

This paper establishes a humanized mouse model of glioblastoma using patient-derived xenografts to study immune infiltration and tumor heterogeneity, finding immune cell profiles similar to recurrent human GBM.

This study uses a high-diversity barcoded HIV library to analyze viral expression and fate determination at the single-cell level, revealing splicing isoforms and translation efficiency.

This paper shows that delayed CCR5 expression after memory formation limits the temporal window for linking memories by reducing neuronal overlap in mice.