Author

Madison T Blucas

University of Alabama at Birmingham

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Organism:human· 1 Organism:mouse· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Chloe E JepsoniD· 2 shared Masakazu KamataiD· 2 shared Anusha Manda· 1 shared Charles J. KuhlmanniD· 1 shared Erwin G. Van MeiriD· 1 shared Fatema M Suleiman· 1 shared Jun TakeiiD· 1 shared Ken FurudateiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersImmunology

Chloe E JepsonORCID

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2 papers

Recent·Most cited

JNK knockdown enhances CAR-T cell cytotoxicity

Charles J. Kuhlmann, Chloe E Jepson, Madison T Blucas, Fatema M Suleiman, Anusha Manda, Yoshiko N Kamata, Masakazu Kamata

This study shows that knocking down JNK in CAR-T cells increases their cytotoxicity against ovarian cancer by enhancing granzyme B expression through NFATc1.

bioRxiv · Aug 14, 2025 · PreprintImmunology

Exploring the immune environment of glioblastoma through single-cell RNA sequencing in humanized mouse models

Jun Takei, Ken Furudate, Yoshiko Nagaoka-Kamata, Opeyemi Iwaloye, Chloe E Jepson, Madison T Blucas, Kiyotaka Saito, Robert S. Welner, Erwin G. Van Meir, Masakazu Kamata, Satoru Osuka

This paper establishes a humanized mouse model of glioblastoma using patient-derived xenografts to study immune infiltration and tumor heterogeneity, finding immune cell profiles similar to recurrent human GBM.

bioRxiv · May 17, 2025 · PreprintImmunology