Author

Filipe Branco dos Santos

University of AmsterdamORCID 0000-0002-4268-8080Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Approach:experimental assay· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Alex Toftgaard NielseniD· 1 shared Anisha GoeliD· 1 shared Anne de JongiD· 1 shared Anne Hesseling· 1 shared Bas TeusinkiD· 1 shared Bert PoolmaniD· 1 shared Bruno Sommer FerreiraiD· 1 shared Claire E. Price· 1 shared

Activity by Year

2017-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperSystems Biology

Alex Toftgaard NielsenORCID

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2 papers

Recent·Most cited

A metabolic reconstruction of Lactobacillus reuteri JCM 1112 and analysis of its potential as a cell factory

Thordis Kristjansdottir, Elleke F. Bosma, Filipe Branco dos Santos, Emre Özdemir, Markus J. Herrgård, Lucas França, Bruno Sommer Ferreira, Alex Toftgaard Nielsen, Steinn Guðmundsson

The paper reconstructs and validates a genome-scale metabolic model for Lactobacillus reuteri JCM 1112T, demonstrating its accuracy in predicting metabolic behavior and identifying strategies for metabolic engineering.

Microbial Cell Factories · Oct 29, 2019Peer-reviewedSystems Biology

Glucose limitation in Lactococcus shapes a single-peaked fitness landscape exposing membrane occupancy as a constraint

Claire E. Price, Filipe Branco dos Santos, Anne Hesseling, Jaakko J. Uusitalo, Herwig Bachmann, Vera Benavente, Anisha Goel, Jan Berkhout, Frank J. Bruggeman, ‪Siewert J. Marrink, Manolo Montalban-Lopez, Anne de Jong, Jan Kok, Douwe Molenaar B, Bert Poolman, , Oscar Paul Kuipers

The paper shows a mutation in CcpA improves fitness in Lactococcus lactis by reprogramming transporters, revealing membrane occupancy as a constraint.

bioRxiv · Jun 8, 2017 · PreprintGenomics