CATSPERβ--δ Interaction Governs Hierarchical CatSper Holo-complex Assembly and is Essential for Male Fertility
Jong‐Nam Oh, Huafeng Wang, Tse-en Wang, Xiaofang Huang, Leonard K. Kaczmarek, Jean‐Ju Chung
bioRxiv · Aug 7, 2026 · PreprintCell Biology
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Yale UniversityORCID 0000-0002-7326-4379Unclaimed ORCID profile · follow to get notified of new preprints
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Jong‐Nam Oh, Huafeng Wang, Tse-en Wang, Xiaofang Huang, Leonard K. Kaczmarek, Jean‐Ju Chung
bioRxiv · Aug 7, 2026 · PreprintCell Biology
Jae Yeon Hwang, Huafeng Wang, Jong‐Nam Oh, Jingon Kim, Sarah F Finnegan, Niels Erik Skakkebæk, Jean‐Ju Chung
This study identifies the essential role of CATSPERε extracellular domains in assembling the CatSper channel complex and modulating sperm hyperactivation and fertilization.
Science Advances · Jan 28, 2026Peer-reviewedCell Biology
Kimberly Griffin, Benjamin William Walters, Haixin Li, Huafeng Wang, Giulia Biancon, Toma Tebaldi, Carolyn Baltazar Kaya, Jean E. Kanyo, TuKiet T. Lam, Andy L. Cox, Stephanie Halene, Jean‐Ju Chung, Bluma J. Lesch
This study identifies a nuclear role for AGO2 in spermatogenesis, showing it enhances protein expression by interacting with splicing and chromatin factors.
Genome Research · Sep 1, 2022Peer-reviewedDevelopmental Biology