Sofie Nyström

SARS-CoV-2 spike protein amyloid fibrils impair fibrin formation and fibrinolysis

This study investigates how specific SARS-CoV-2 Spike protein amyloid fibrils impair fibrin formation and fibrinolysis, contributing to Long COVID pathophysiology.

Divergent age-dependent conformational rearrangement within Aβ-amyloid deposits in APP23, APPPS1, and AppNL-F mice

This paper compares Aβ fibril structures in three mouse models of Alzheimer's disease, finding age-dependent differences in plaque morphology and polymorph maturation.

SARS-CoV-2 Spike amyloid fibrils specifically and selectively accelerates amyloid fibril formation of human prion protein and the amyloid β peptide

This study shows that SARS-CoV-2 spike amyloid fibrils accelerate amyloid formation of human prion protein and amyloid β peptide in vitro, suggesting a potential mechanism linking COVID-19 to neurodegenerative diseases.