Marie-Ève Picard

The paper shows that resistance mutations to antifungal drugs are conserved across fungal species but epistasis limits their transferability.

The paper duplicates and evolves an homodimeric enzyme to show that compensatory mutations can lead to functional heteromers through subfunctionalization.

This study identifies AbiV as an RNase in the bacterial antiphage system AbiV, revealing its structure, function, and mechanism of action.