Author

Francesco Sarnari

Inserm

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Aboud SakkaliD· 1 shared Aldo Pastore· 1 shared Alexandra TachtsidiiD· 1 shared Anna Luisa Di StefanoiD· 1 shared Annarita MiccioiD· 1 shared Anne H. M. GalyiD· 1 shared Bruce J. WestiD· 1 shared Carlo GambaccianiiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMolecular Biology

Aboud SakkalORCID

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2 papers

Recent·Most cited

CRISPR-Mediated Linearization of IDLV Donor Enables Precise Targeted Integration in Human Hematopoietic Stem Cells

Giulia Scalisi, Aboud Sakkal, Laurie Lacombe, Francesco Sarnari, Marine Rouillon, Michela Rosiello, Alexandra Tachtsidi, Paola Galbiati, Guillaume Corre, Julie Oustelandt, Giulia Pavani, Marine Laurent, Mike A. Firth, Marie As, Marcello Maresca, , Mario Amendola

This paper introduces TILV, a CRISPR-assisted method for precise targeted integration of transgenes in human hematopoietic stem cells using IDLV donors, showing improved efficiency and minimal impact on cell viability.

bioRxiv · Jun 17, 2026 · PreprintMolecular Biology

From Single-Cell Emergent Behaviors to Clinical Outcome: PTEN-driven Migratory Efficiency as a Potential New Vulnerability in Glioblastoma

Mariangela Morelli, Gianmarco Ferri, Francesca Lessi, Francesca Di Lorenzo, Sara Franceschi, Francesca Marchetto, Gabriele Tancreda, Tiziano Vadi, Francesco Sarnari, Tim Hohmann, Francesco Pieri, Carlo Gambacciani, Francesco Pasqualetti, Yawer Hussain Shah, Jace Singh, , Chiara Maria Mazzanti

This study identifies PTEN gain-of-function mutations as linked to increased migratory efficiency in glioblastoma cells, correlating with poorer patient survival.

bioRxiv · Mar 20, 2026 · PreprintCancer Biology