Michael Wu

This study shows that intra-arterial DNase therapy improves stroke outcomes in aged mice by enhancing reperfusion and reducing NETs.

This study creates a novel SCA13 mouse model with a R424H mutation, showing motor deficits, Purkinje cell loss, cerebellar inflammation, and atrophy, linking neuroinflammation to neurodegeneration.

This paper presents a novel BAC mouse model of SCA13 with cerebellar hypoplasia, tremor, and ataxic gait, mimicking human disease features.