Bingbing Xu

Cis mutagenesis in vivo reveals extensive noncanonical functions of Dscam1 isoforms in neuronal wiring

The paper uses cis mutations in Dscam1 to show noncanonical roles of isoform diversity in neuronal wiring, revealing distinct phenotypic defects in different neuron types.

Self-avoidance alone does not explain the function of Dscam1 in mushroom body axonal wiring

The paper shows that reduced Dscam1 isoform diversity, not just self-avoidance, causes defects in mushroom body axonal wiring in Drosophila.

Intron-targeted mutagenesis reveals roles for Dscam1 RNA pairing-mediated splicing bias in neuronal wiring

The paper shows that specific Dscam1 isoform splicing biases are required for precise mushroom body axonal wiring in Drosophila, with variable domain-specific effects.