Jianhua Huang

The paper identifies differentially expressed lncRNAs and mRNAs in preeclampsia plasma, finds dysregulation of lncRNA-uc002ywy.3/miRNA-4498, and links it to the PD-1/PD-L1 pathway.

The paper uses cis mutations in Dscam1 to show noncanonical roles of isoform diversity in neuronal wiring, revealing distinct phenotypic defects in different neuron types.

The paper uses single-cell RNA sequencing to determine expression profiles of Drosophila ovarian Follicle Stem Cells and neighboring cell types, revealing AP progression and candidate genes involved in signaling pathways.

The paper shows that reduced Dscam1 isoform diversity, not just self-avoidance, causes defects in mushroom body axonal wiring in Drosophila.

The paper analyzes single-cell expression variability in homogeneous human cell populations, finding it widespread, heritable, and functionally relevant.

The paper shows that specific Dscam1 isoform splicing biases are required for precise mushroom body axonal wiring in Drosophila, with variable domain-specific effects.