CryoEM structures of the multimeric secreted NS1, a major factor for dengue hemorrhagic fever
Bo Shu, Justin S. G. Ooi, Aaron Wai Kit Tan, Thiam‐Seng Ng, Wanwisa Dejnirattisai, Juthathip Mongkolsapaya, G. Fibriansah, Jian R. Shi, V.A. Kostyuchenko, Gavin Robert Screaton, Shee‐Mei Lok
This study determines the tetrameric and hexameric structures of secreted dengue NS1, revealing their quaternary organization and how antibody binding affects their stability.
Nature Communications · Nov 8, 2022Peer-reviewedMolecular Biology