Wanwisa Dejnirattisai

The paper disrupts the synergistic immune evasion of dengue virus by targeting IFIT1-STAT2, resulting in an attenuated virus that enhances innate immune priming.

The paper reprocesses SARS-CoV-2 genomic data to correct systematic errors in phylogenies using a novel assembly tool, resulting in a cleaner global tree of 4.47 million samples.

The paper compares SARS-CoV-2 antigenicity across assays and in human and animal model sera, finding similar immunodominance patterns and antigenic maps but differences in titer magnitude and assay-specific fold change.

This study determines the tetrameric and hexameric structures of secreted dengue NS1, revealing their quaternary organization and how antibody binding affects their stability.