Louis Vermeulen

FFPERescuer uses deep learning to improve gene expression reconstruction from degraded FFPE samples, achieving high accuracy and enhancing cancer subtyping.

This study uses single-cell RNA sequencing to analyze immune landscapes in humanized mice with colorectal cancer, showing complex human-like immune infiltrates and subtype-specific immune differences.

This study shows that specific Apc mutations modulate Wnt signaling activity in intestinal organoids, with optimal Wnt levels selected through additional mutations and associated transcriptional and metabolic changes.

The paper identifies a novel transient SOX9+ pericentral hepatocyte population in acute liver injury that mediates early tissue repair and immune modulation.

This study identifies the Jag2/Notch1 signaling axis as critical for sebaceous gland differentiation and progenitor cell regulation in adult skin.