BiochemistryJournal of the American Chemical SocietyPeer-reviewed
Bis-hydroxylation of Homocitrulline Catalyzed by a Multinuclear Nonheme Iron-Dependent Oxidative Enzyme during RiPP Biosynthesis
Dayna P Hebron, Tucker J. Shriver, Joshua J. Ziarek, Amy C. Rosenzweig
The paper identifies a novel RiPP biosynthetic pathway in Streptomyces thermodiastaticus involving a YcaO-TfuA pair, a carbamoyltransferase, and a MNIO enzyme that bis-hydroxylates homocitrulline.
DOI 10.1021/jacs.6c09029