Kana Ishimatsu

The paper uses single-cell RNA sequencing to analyze inner ear development in zebrafish, identifying cell states and genes involved in sensory patches, semicircular canals, and endolymphatic sac formation.

The paper shows that Scube2 and Shh form a feedback loop that enables the Shh morphogen gradient to scale with tissue size in the ventral neural tube.

The paper shows that a dynamically scaling gradient in the presomitic mesoderm regulates somite size control in zebrafish embryos.