Ian A. Swinburne

The paper introduces MOSAIC, a multimodal adaptive optical microscope that enables non-invasive imaging across biological scales in live specimens.

The paper uses single-cell RNA sequencing to analyze inner ear development in zebrafish, identifying cell states and genes involved in sensory patches, semicircular canals, and endolymphatic sac formation.

This study shows that microtubules regulate Langerhans cell phagocytosis and directed migration in zebrafish skin by controlling dendrite morphology and navigation.

The paper shows that Scube2 and Shh form a feedback loop that enables the Shh morphogen gradient to scale with tissue size in the ventral neural tube.

The paper investigates how zebrafish inner ear size is controlled through hydraulic feedback mechanisms involving fluid pressure and transport.

The paper identifies a pressure relief valve in the endolymphatic sac of zebrafish larvae that regulates inner ear pressure through dynamic lamellar junctions.

The paper develops a method to image subcellular dynamics in vivo using lattice light sheet microscopy and adaptive optics, revealing phenotypic diversity across organisms and developmental stages.