Structural Mechanism of Prestin-Membrane Mechanotransduction
Navid Bavi, Patrick Roman Haller, Kazuaki Homma, Xiaoxuan Lin, Wieslawa M. Milewski, Minglei Zhao, Tobin R. Sosnick, Eduardo Perozo
This study reveals how prestin translates membrane tension into charge and motor movement during sound-evoked vibrations through structural analysis and complementary experiments.
bioRxiv · Oct 31, 2025 · PreprintBiophysics