Tjeerd M. H. Dijkstra

The paper introduces a non-parametric synergy model, Hand-GP, which outperforms existing parametric models in assessing drug and toxin combination effects.

EPIFANY improves protein inference accuracy and efficiency by combining loopy belief propagation with convolution trees, outperforming existing methods on benchmark data.

The paper presents a large-scale cancer pharmacogenomic screen with 11,576 experiments on 910 drug combinations across 85 cancer cell lines, enabling crowd-sourced prediction of synergistic drug pairs and biomarkers.