Poonam Singh Thakur

This study shows that chlorogenic acid provides neuroprotection in vitro but not in vivo in a chronic Parkinson's disease mouse model.

The paper identifies shared and sex-specific lipidomic changes in brain and plasma of Parkinson's disease models and patients, showing peripheral lipid signatures reflect CNS pathology.

This study shows that glycated alpha-synuclein assemblies cause distinct Parkinson's disease pathology in mice, including earlier onset of motor symptoms and increased neuroinflammation.

The paper shows that surviving DA SN neurons after lesion recovery exhibit full in vivo firing range through Kv4.3-mediated pacemaker plasticity.

This paper develops a mouse model of Parkinson's disease by overexpressing α-synuclein and demonstrates neuroprotection with PD180970.

The paper shows that α-synuclein aggregates disrupt pacemaking in vulnerable nigrostriatal dopamine neurons via K-ATP channels, contributing to Parkinson's disease pathogenesis.