Jennifer J. Westendorf

This study investigates the in vivo role of CRTC2/3 in osteoblasts by analyzing bone phenotype and gene expression changes in conditional knockout mice.

The paper identifies key cell types and genes involved in skeletal disease using single-cell analysis and validates their roles in mouse models.

This study shows that Phlpp1 deficiency increases Pth1r expression and signaling, leading to longer bones and thicker growth plates in mice.