Author

Shruti Garg

University of ManchesterORCID 0000-0002-4472-4583Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Organism:human· 4 Approach:statistical model· 4 Assay:imaging· 3 Organism:Drosophila· 2 Approach:experimental assay· 2 Research Focus:benchmarking· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Caroline Lea‐CarnalliD· 4 shared Marta Czime LitwińczukiD· 4 shared Nelson J. Trujillo‐BarretoiD· 3 shared Alex DysoniD· 2 shared D. Gareth EvansiD· 2 shared Richard BainesiD· 2 shared Gorana PobriciD· 1 shared Jason R. TayloriD· 1 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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4 shared papersNeuroscience

Caroline Lea‐CarnallORCID

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Altered Aperiodic EEG Activity in Adolescents with Neurofibromatosis Type 1

Marta Czime Litwińczuk, Thomas Donoghue, Jason R. Taylor, Gorana Pobric, Caroline Lea‐Carnall, Shruti Garg

This study finds that adolescents with Neurofibromatosis Type 1 have higher aperiodic EEG activity, consistent with increased inhibitory tone, but no cognitive performance differences.

bioRxiv · Oct 7, 2026 · PreprintNeuroscience

Fronto-parietal effective connectivity during working memory in Neurofibromatosis Type 1 adolescents and neurotypical controls

Marta Czime Litwińczuk, Shruti Garg, Caroline Lea‐Carnall, Nelson J. Trujillo‐Barreto

This study uses fMRI and DCMs to compare frontoparietal network connectivity during working memory in NF1 adolescents and neurotypical controls, finding increased intrinsic connectivity in NF1 with mixed modulatory effects.

Human Brain Mapping · Feb 1, 2026Peer-reviewedNeuroscience

Working memory impairments in Neurofibromatosis Type 1 are explained by disrupted functional connectivity and network controllability

Marta Czime Litwińczuk, Nelson J. Trujillo‐Barreto, JeYoung Jung, Yuping Yang, Shruti Garg, Caroline Lea‐Carnall

This study identifies altered functional connectivity and network controllability in NF1 adolescents during working memory tasks, which predict cognitive performance and distinguish NF1 from controls.

bioRxiv · Apr 10, 2025 · PreprintNeuroscience

Effects of non-invasive brain stimulation on effective connectivity during working memory task in Neurofibromatosis Type 1 patients

Marta Czime Litwińczuk, Shruti Garg, Stephen R. Williams, Jonathan Green, Caroline Lea‐Carnall, Nelson J. Trujillo‐Barreto

This study investigates how non-invasive brain stimulation affects effective connectivity during working memory in NF1 patients, finding changes in fronto-striatal connectivity and associations with GABA levels.

bioRxiv · Oct 16, 2024 · PreprintNeuroscience

A targeted, low-throughput compound screen in a Drosophila model of Neurofibromatosis Type 1 identifies simvastatin and BMS-204352 as potential therapies for autism spectrum disorder (ASD).

Alex Dyson, Megan Ryan, Shruti Garg, D. Gareth Evans, Richard Baines

This study identifies simvastatin and BMS-204352 as potential ASD therapies in a Drosophila Nf1 model by reducing tactile hypersensitivity and synaptic transmission defects.

eNeuro · Apr 26, 2023Peer-reviewedNeuroscience

Loss of NF1 causes tactile hypersensitivity and impaired synaptic transmission in a Drosophila model of autism spectrum disorder

Alex Dyson, Shruti Garg, D. Gareth Evans, Richard Baines

This study shows that loss of NF1 in Drosophila causes tactile hypersensitivity and synaptic transmission deficits, similar to ASD features, and these effects are rescued by knocking down Ras proteins.

bioRxiv · Mar 4, 2022 · PreprintNeuroscience