A targeted, low-throughput compound screen in a Drosophila model of Neurofibromatosis Type 1 identifies simvastatin and BMS-204352 as potential therapies for autism spectrum disorder (ASD).
Alex Dyson, Megan Ryan, Shruti Garg, D. Gareth Evans, Richard Baines
This study identifies simvastatin and BMS-204352 as potential ASD therapies in a Drosophila Nf1 model by reducing tactile hypersensitivity and synaptic transmission defects.
eNeuro · Apr 26, 2023Peer-reviewedNeuroscience