Marco Terenzio

This study shows that aging reduces axonal translation in sensory neurons, linked to decreased mitochondrial activity and ATP levels, which can be partially reversed by increasing ATP synthesis.

The paper shows that local translation sustains synaptic function in impaired Wallerian degeneration by identifying mTOR and related pathways involved in protein synthesis and calcium homeostasis.

This study shows DYNLRB1 is essential for dynein-mediated transport and sensory neuron survival, with loss-of-function leading to embryonic lethality and neuronal deficits.