Agostina Di Pizio

The paper identifies multiple mTOR RNA localization signals in the 5'UTR and 3'UTR that regulate subcellular mTOR localization, protein synthesis, and axonal growth in mice.

This paper develops AAV-STITCH, a method to target neuroblastoma cells using anti-GD2 ScFv coupled to AAV capsids, showing selective transduction and tumor suppression in mouse models.

This study shows PTBP1 is expressed in adult sensory and motor neurons, with increased axonal levels after injury, affecting axon outgrowth and sensation.

This paper describes a conditional Dync1h1 mouse model to study dynein's role in neuronal growth and neurological disorders, finding accelerated growth and mild impairments in heterozygous animals.

This study shows DYNLRB1 is essential for dynein-mediated transport and sensory neuron survival, with loss-of-function leading to embryonic lethality and neuronal deficits.