ImmunologyProceedings of the National Academy of SciencesPeer-reviewed
Therapeutic remodeling of the tuberculosis granuloma with 1-methyl-D-tryptophan enhances CD8+ T cell-macrophage interactions
Erin McCaffrey, Alea C. Delmastro, Bindu Singh…·Smriti Mehra
This study shows that D-1MT treatment enhances CD8+ T cell infiltration and interactions with macrophages in TB granulomas, improving immune control of Mtb.
DOI 10.1073/pnas.2528104123