Author

L.G. Pedersen

National Institute of Environmental Health SciencesORCID 0000-0002-4488-4077Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:protein structure prediction· 2 Organism:bacteria (other)· 1 Assay:cryo-EM· 1 Approach:experimental assay· 1 Assay:protein structure· 1 Approach:simulation· 1 Approach:statistical model· 1

Frequent Co-Authors

Andrea M. KaminskiiD· 2 shared Alan E. TomkinsoniD· 1 shared Alex VogtiD· 1 shared Danny LaurentiD· 1 shared Jason G. Williams· 1 shared Lalith PereraiD· 1 shared Libertad Garcı́a-VilladaiD· 1 shared Natalya P. DegtyarevaiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiophysics

Andrea M. KaminskiORCID

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2 papers

Recent·Most cited

BiophysicsNature CommunicationsPeer-reviewedSep 9, 2026

End Processing in NHEJ by Polymerase {lambda} and PNKP is coordinated during short-range synapsis

Alex Vogt, Andrea M. Kaminski, Jason G. Williams…·Yuan He

The paper determines the cryo-EM structure of Pol λ bound to the short-range synaptic complex, revealing its recruitment mechanism and coordinated activity with PNKP in NHEJ end processing.

3 citations

cryo-EMexperimental assay

𝕏 PostBluesky

Molecular BiologyBiomoleculesPeer-reviewedFeb 18, 2026

Structural and Computational Analysis of Pseudomonas Aeruginosa DNA Gyrase Reveals Molecular Characteristics That May Contribute to Ciprofloxacin Resistance

Lalith Perera, Libertad Garcı́a-Villada, Andrea M. Kaminski…·Paul W. Doetsch

The paper analyzes the molecular mechanisms of ciprofloxacin resistance in Pseudomonas aeruginosa by solving the gyrase structure and performing MD simulations of wild-type and mutant systems.

2 citations

bacteria (other)protein structure

𝕏 PostBluesky