Helen R Horkan

This study identifies a positive feedback loop between germ cells and gonads in cnidarians that induces and maintains sexual reproduction through Gls signaling and Tfap2 activation.

This study shows that Hydractinia symbiolongicarpus regenerates whole bodies from cell suspensions through i-cell progeny, revealing a link between regeneration and embryonic development.

The paper constructs a Hydractinia cell atlas to study the cellular and molecular mechanisms of coloniality, finding that distinct colony parts are defined by combinations of shared cell types and rare innovations.

This study shows that senescent cell signals reprogram somatic cells into stem cells, enabling whole-body regeneration in cnidarians.

This study shows that adult stem cells in the cnidarian Hydractinia symbiolongicarpus are pluripotent and can generate a fully functional, sexually competent individual.