Uri Frank A

This study identifies a positive feedback loop between germ cells and gonads in cnidarians that induces and maintains sexual reproduction through Gls signaling and Tfap2 activation.

This study shows that Hydractinia symbiolongicarpus regenerates whole bodies from cell suspensions through i-cell progeny, revealing a link between regeneration and embryonic development.

The paper constructs a Hydractinia cell atlas to study the cellular and molecular mechanisms of coloniality, finding that distinct colony parts are defined by combinations of shared cell types and rare innovations.

This study characterizes the genome and single-cell transcriptome of Hydractinia, revealing that its stem cells use a conserved gene toolkit shared with all animals.

This study shows that random genomic 6mA accumulation in early Hydractinia embryos delays zygotic transcription initiation by inhibiting gene expression.

This study shows that senescent cell signals reprogram somatic cells into stem cells, enabling whole-body regeneration in cnidarians.

This study shows that adult stem cells in the cnidarian Hydractinia symbiolongicarpus are pluripotent and can generate a fully functional, sexually competent individual.

This study investigates SoxB-driven neurogenesis in the cnidarian Hydractinia symbiolongicarpus, showing sequential SoxB gene action and defects upon knockdown.

The paper shows that spH2B variants in Hydractinia sperm stabilize chromatin and block transcription without significantly compacting chromatin, supporting their role in sperm buoyancy.

This paper introduces CRISPR/Cas9-mediated gene knockin in Hydractinia symbiolongicarpus, enabling stable transgene integration and germline transmission for functional genomics studies.