Malika Aïd

This study identifies early innate immune signatures following Ad26.COV2.S vaccination that correlate with vaccine durability and protective efficacy in rhesus macaques and humans.

This study identifies the origin and dynamics of viral rebound in SIV-infected macaques after ART discontinuation, showing local tissue replication and systemic expansion of clonal lineages.

This study uses scRNA-seq to analyze immune changes in SIV-infected rhesus macaques over time, revealing immune shifts during infection and ART, and identifying transcriptional signatures linked to immune dysregulation and treatment outcomes.

This study compares the immunological profiles and protective efficacy of Ad5, mRNA, and protein vaccines in mice, showing differences in antigen kinetics, immune responses, and performance based on serostatus and dosing regimen.

This study examines the early spatiotemporal immune response to Ad26 vaccination in mice, showing rapid innate activation in tissues and blood that correlates with later memory CD8+ T cell responses.

This study shows that ZIKV-117, a neutralizing monoclonal antibody, provides complete protection against ZIKV challenge in rhesus macaques at a low dose.

The paper identifies persistent activation of inflammatory pathways in Long Covid patients compared to controls and links acute infection severity to Long Covid development.