Shiyi Li

Development of a cross-protective common cold coronavirus vaccine

This paper develops an mRNA vaccine against OC43, a common cold coronavirus, showing cross-protection against related viruses like MHV-A59.

Dosing and Serostatus Shape the Efficacy of Adenovirus, mRNA, and Protein Vaccines

This study compares the immunological profiles and protective efficacy of Ad5, mRNA, and protein vaccines in mice, showing differences in antigen kinetics, immune responses, and performance based on serostatus and dosing regimen.

Robust identification of extrachromosomal DNA and genetic variants using multiple genetic abnormality sequencing (MGA-Seq)

This study introduces MGA-Seq, a method to detect multiple genomic abnormalities, and finds that focal amplification in tumors is heterogeneous and reveals ecDNA network architecture.

High-resolution Dynamic Human Brain Neural Activity Recording Using 3T MRI

This paper introduces TRIGGER, a 3T MRI technique for high-resolution neural activity recording in awake humans, showing millisecond temporal resolution and hemispheric response timing.