Author

Huikang Qian

Case Western Reserve UniversityORCID 0000-0002-4502-196XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 2

Frequent Co-Authors

Abhinav P. AcharyaiD· 2 shared Abhirami Suresh· 1 shared Abhirami ThumsiiD· 1 shared Abigail Raffner BassoniD· 1 shared Bo ZhangiD· 1 shared Brenden P. WheeleriD· 1 shared Carlie Charron· 1 shared Carlo De SalvoiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersImmunology

Abhinav P. AcharyaORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Mesaconic acid delivery via biomaterials and engineered probiotics to the gut reduces inflammation in Crohn's Diseases mouse models

Huikang Qian, Drishtant Singh, Zixuan Chen, Wenfei Zhao, Bo Zhang, Taravat Knodaei, Abhirami Thumsi, Sanmoy Pathak, Abhirami Suresh, Paola Menghini, Julia Schiek, Viveka Rabara, Carlo De Salvo, Harihara Baskaran, Yuji Aso, , Abhinav P. Acharya

The paper develops two strategies to increase mesaconate levels in the gut to reduce inflammation in Crohn's Disease mouse models.

bioRxiv · Oct 7, 2026 · PreprintImmunology

Development of itaconate polymer microparticles for intracellular regulation of pro-inflammatory macrophage activation

Kaitlyn E. Woodworth, Zachary S.C.S. Froom, Natasha D. Osborne, Christian N. Rempe, Brenden P. Wheeler, Kyle Medd, Neal I. Callaghan, Huikang Qian, Abhinav P. Acharya, Carlie Charron, Locke Davenport Huyer

This paper develops itaconate polymer microparticles for intracellular delivery of itaconate to regulate macrophage inflammation, showing reduced cytotoxicity and metabolic changes.

Advanced Healthcare Materials · Apr 4, 2025Peer-reviewedBioengineering