Mika A. P. Kähönen

This study identifies 139 common and 4 rare genetic variants associated with type 2 diabetes through GWAS and integrates gene expression and epigenomic data to highlight potential functional genes and regulatory mechanisms.

The paper identifies gene targets for brain-related traits using transcriptomic and methylomic data from blood, finding strong correlations between genetic effects in brain and blood tissues.

This study identifies 99 genetic loci associated with general cognitive function using data from 280,360 individuals, finding genes linked to brain structure and neurodegenerative disorders.

This paper introduces SAPPHO methods to detect pleiotropy in GWAS by modeling shared patterns of genetic associations, finding 16 additional and 124 novel loci in meta-analysis.

This study identifies 47 novel genetic loci associated with PR interval through genome-wide association meta-analysis across multiple populations.

The paper integrates transcriptomic, metabolomic, and genomic data to identify gene networks and their genetic regulation linked to immune function and circulating metabolites.

This study investigates the association between CpG methylation and educational attainment, finding limited significant associations that may be influenced by confounding factors.

This study examines the metabolic effects of alcohol consumption in young adults, finding associations with multiple cardiometabolic risk markers and a complex metabolic signature.

This study identifies 17 new genetic loci associated with circulating cytokine and growth factor concentrations in Finns, linking them to immune-related diseases and potential drug targets.

This study links elevated glycoprotein acetyls (GlycA) to chronic inflammation and microbial infection risk using integrative omics and health records.