Peter Würtz

The paper develops metabolomic risk scores from half a million blood samples to predict 12 common diseases, showing they outperform polygenic scores and benefit from repeat measurements.

The paper performs metabolite GWAS on UK Biobank data to investigate pleiotropy and genetic correlation, finding pathway-relevant genes and contrasting variant effects.

This study identifies genetic variants with pleiotropic effects on cytokines and related traits using a multivariate genome-wide association analysis.

The paper identifies alpha-1 antitrypsin as a key contributor to GlycA's predictive power for disease risk and mortality across multiple conditions.

This study examines the metabolic effects of ANGPTL3 deficiency in fasting and postprandial states, finding reduced lipoprotein cholesterol and increased ketone bodies in carriers.

The paper integrates transcriptomic, metabolomic, and genomic data to identify gene networks and their genetic regulation linked to immune function and circulating metabolites.

This study identifies 17 new genetic loci associated with circulating cytokine and growth factor concentrations in Finns, linking them to immune-related diseases and potential drug targets.

This study examines the metabolic effects of alcohol consumption in young adults, finding associations with multiple cardiometabolic risk markers and a complex metabolic signature.

This study links elevated glycoprotein acetyls (GlycA) to chronic inflammation and microbial infection risk using integrative omics and health records.