ATRAID regulates the action of nitrogen-containing bisphosphonates on bone.
Lauren E. Surface, Damon T. Burrow, Jinmei Li, Jiwoong Park, Sandeep Kumar, Cheng Lyu, Niki Song, Zhou Yu, Abbhirami Rajagopal, Yangjin Bae, Brendan Lee, Steven R. Mumm, C. Charles Gu, Jonathan C. Baker, Mahshid Mohseni, , Timothy R. Peterson
The paper identifies ATRAID as a gene critical for the response to nitrogen-containing bisphosphonates, showing its role in drug efficacy and resistance in osteoporosis.
Science Translational Medicine · May 20, 2020Peer-reviewedGenomics