Jiwoong Park

The paper proposes using cell fitness as a universal phenotype to prioritize gene and drug targets in disease research, showing its broad applicability across diseases and cost-effectiveness.

This paper identifies BIOIO-1001 as a dual mTOR/NAD+ acting gerotherapy that reduces metabolic derangements, inflammation, and fibrosis in NASH and ALS models.

The paper identifies ATRAID as a gene critical for the response to nitrogen-containing bisphosphonates, showing its role in drug efficacy and resistance in osteoporosis.

This study identifies that multiple cationic amphipathic drugs (CADs) share molecular similarities with chloroquine and inhibit sphingolipid biosynthesis, suggesting their potential as antiviral agents against diverse pathogens including SARS-CoV-2.