Author

Zhou Yu

Brigham and Women's HospitalORCID 0000-0003-3213-4583Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Zhou Yu4 papers · University of Southern California

Biology Disciplines

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Genomics· 1 Immunology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Abbhirami Rajagopal· 1 shared Amrita Dhindsa· 1 shared Andrian GutuiD· 1 shared Brendan LeeiD· 1 shared Brian CoventryiD· 1 shared C. Charles GuiD· 1 shared Cheng LyuiD· 1 shared Chris M. McAndrewiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperGenomics

Abbhirami Rajagopal

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3 papers

Recent·Most cited

ImmunologybioRxivPreprintJun 4, 2026

Systems-Scale Structural Modeling Reveals the Germline Architecture of Immunodominance

Ellen L. Shrock, Eric Sun, Amrita Dhindsa…·David A. Baker

This study identifies germline-encoded features as the primary driver of immunodominance in antibody responses to SARS-CoV-2, using structural modeling and mutational analysis.

DOI 10.64898/2026.06.02.729678

𝕏 PostBluesky

NeuroscienceeLifePeer-reviewedJun 2, 2025

Activity-dependent synapse elimination requires caspase-3 activation

Zhou Yu, Andrian Gutu, Namsoo Kim, Erin K. O’Shea

This study shows that caspase-3 activation is essential for activity-dependent synapse elimination during development and in Alzheimer's disease models.

5 citations

mouseexperimental assay

𝕏 PostBluesky

GenomicsScience Translational MedicinePeer-reviewedMay 20, 2020

ATRAID regulates the action of nitrogen-containing bisphosphonates on bone.

Lauren E. Surface, Damon T. Burrow, Jinmei Li…·Timothy R. Peterson

The paper identifies ATRAID as a gene critical for the response to nitrogen-containing bisphosphonates, showing its role in drug efficacy and resistance in osteoporosis.

25 citations

𝕏 PostBluesky